SLCTR/2018/030尚未招募3 期
Oxidative stress in Chronic Kidney Disease of unknown aetiology (CKDu) and the efficacy and safety of vitamin C and vitamin E in slowing the progression of early stages of CKDu in Sri Lanka. – A Double Blinded Placebo Controlled Randomized Clinical Trial
niversity of Colombo, Sri Lanka0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Male and female patients aged between 18 and 45 years
- •2. Diagnosed with stages 1-3 of chronic kidney disease of unknown origin, as determined by
- •Albuminuria (ACR >30 mg/g)
- •Decreased GFR
- •Lower serum levels of liver enzymes
- •Increased Beta-2 microglobulin (B2M) concentration
- •Low serum bilirubin level
排除标准
- •1. Patients with renal insufficiency with a potentially reversible cause such as: malignant hypertension, urinary tract infection, hypercalcemia, drug-induced nephrotoxic effects systemic diseases such as connective-tissue diseases.
- •2. Patients on drugs which are known to be used as antioxidants, such as Coenzyme Q10 (ubiquinone), Fish Oil (Omega – 3 polyunsaturated fatty acids), Vitamin B complex 100, Vitamin B12, Vitamin D3, Vitamin C, Vitamin E.
- •3. Patients with Acute myocardial infarction or cerebrovascular accident in the previous 6 months.
- •4. Patients with chronic diseases (e.g. bronchial asthma and chronic liver cell disease).
- •5. Drug or alcohol abused Patients.
- •6. Patients who are pregnant or breastfeeding.
- •7. Patients who are not willing to participate in the study.
- •8. Patients with Drug allergies.
- •9. Patients with CKDu in stage 4 & 5.
研究者
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