EFFECT OF TRIKANTAKADI CHURN ALONG WITH TRINPANCHMOOL KWATH AND GOKSHURADI GUGGULU ALONG WITH VARUNADI KWATH IN MUTRAGHAT PATIENT. (CHRONIC KIDNEY DISEASE UPTO GRADE 3B).

Phase 2

Conditions: Health Condition 1: N183- Chronic kidney disease, stage 3 (moderate)

Registration Number: CTRI/2024/03/064690

Lead Sponsor: All India Institute of Ayurveda

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1 Patient diagnosed with sign &symptoms of CKD as per standard KDQOL CRITERIA

2 Patient presenting with symptoms of Mutravaha Srotas Dusti Shavyathu Pandu Shwaskricchta.

3 Patients of both gender of age 21 to 70 Groups with confirmed diagnosis of stage up to G3b as per standard KDIGO CRITERIA (I.e eGFR more than 30 and less than 44 ml/min. per 1.73 m2), not having undergone RRT were included.

4.Patients under controlled Diabetes ,Hypertension and anemia with or without conventional therapy

5.Sex Both male and female with irrespective gender.

6.Subjects who able to take medicine orally.

7.Subjects who are willing to sign the informed consent.

8.Subjects who are not registered in any other research project.

Exclusion Criteria

1. Patients suffering from Tuberculosis, Malignancy, Pregnancy and lactation, or any other systemic illness.

2. Uncontrolled diabetes and HTN

3. HIV-associated nephropathy and transplant allograph failure

4. Known case of Renal Artery stenosis.

5. Known case of Neoplasm of Kidney.

6. History of previous kidney transplant.

7. Patients of Congenital Renal Diseases like Autosomal dominant and Recessive Polycystic Kidney disease, Congenital Nephrotic syndrome (Finnish type), Alport’s syndrome, Fabry ‘s disease and juvenile Nephronophthisis.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in KFT, eGFR, CBC with ESR ,FBS,PPBS,Hba1c, Urine RMTimepoint: day 0, 30 day and 60 day

Secondary Outcome Measures

Name	Time	Method
To improve the quality of life of CKD patient (quality of life KDQOL TM-36 <br/ ><br>Improvement in the classical sign and symptom of mutravaha stroto dushti lakshan.Timepoint: day0, 15th day, 30 day and after 6o day