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临床试验/NCT06915714
NCT06915714已完成不适用

The Prognostic Value of Quantitative Parameters Derived From Dual Scanning of FDG and PSMA PET/CT for Tumor Progression in Patients With Metastatic Hormone-sensitive Prostate Cancer Receiving Novel Hormone Therapy

Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2024年6月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
45
试验地点
1
主要终点
Castration-Resistant Prostate Cancer free survival (CRPC-FS)

研究概览

简要总结

Investigators retrospectively collected data from consecutive patients treated at the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, from October 2020 to March 2024. The inclusion criteria were as follows: (1) patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information; (2) patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment. The exclusion criteria were as follows: (1) patients who received novel hormone therapy or a prostate biopsy prior to PET/CT; (2) patients with other malignancies; (3) patients received hormone therapy without NHT; (4) patients received chemotherapy or radiotherapy prior to or during novel hormone therapy; (5) absence of follow-up data at the hospital.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
Male
接受健康志愿者
否

入选标准

  • •patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information
  • •patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment

排除标准

  • •patients who received novel hormone therapy or a prostate biopsy prior to PET/CT
  • •patients with other malignancies
  • •patients received hormone therapy without novel hormone therapy
  • •patients received chemotherapy or radiotherapy prior to or during novel hormone therapy
  • •absence of follow-up data at our institution

结局指标

主要结局

Castration-Resistant Prostate Cancer free survival (CRPC-FS)

时间窗: From date of the initiation of novel hormone therapy until the date of first documented either PSA or radiography-confirmed progression or date of the last follow-up for any cause, whichever came first, assessed up to 100 months

次要结局

未报告次要终点

研究者

发起方
Sun Yat-sen University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Zheng fufu

Professor, Phd, Md

Sun Yat-sen University

研究点 (1)

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