ISRCTN18274006进行中（未招募）未知

Rates, Risks and Routes to Reduce Vascular Dementia

Academic and Clinical Central Office for Research and Development (ACCORD)0 个研究点目标入组 2,000 人开始时间: 2019年7月29日最近更新: 2024年7月8日

适应症

试验速览

2024 Preprint results in https://doi.org/10.1101/2024.04.30.24306637 (added 21/06/2024)

•Current inclusion criteria as of 17/06/2020:
•1. Patients aged 18 and over
•2. No upper age limit
•3. No severity limit
•4. Ischaemic or spontaneous haemorrhagic (non-traumatic, non-subarachnoid haemorrhage, non-AVM) stroke and transient ischaemic attack (TIA)
•5. Expected to survive at least 12 weeks
•DTI substudy only
•1. Estimated life expectancy >= 1 year
•2. No contraindications to MRI
•3. Patients with capacity to consent at baseline
•COVID-19 substudy: expected to survive 12 weeks is not an inclusion criterion.
•Previous inclusion criteria:
•1. Patients aged 18 and over
•2. No upper age limit
•3. No severity limit
•4. Ischaemic or spontaneous haemorrhagic (non-traumatic, non-subarachnoid haemorrhage, non-AVM) stroke and transient ischaemic attack (TIA)
•5. Expected to survive at least 12 weeks

•1. Inclusion criteria not met
•2. Aneurysmal, traumatic or AVM-associated haemorrhage or subarachnoid haemorrhage
•3. Stroke mimics such as brain tumours
•4. Prior diagnosis of cognitive impairment or dementia is NOT an exclusion criteria

发起方

Academic and Clinical Central Office for Research and Development (ACCORD)