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Clinical Trials/ISRCTN72654148
ISRCTN72654148
Completed
Not Applicable

MACS: Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study

niversity of Toronto Faculty of Medicine Research Office (Canada)0 sites1,900 target enrollmentFebruary 10, 2004
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ConditionsPregnancies at increased risk of preterm birthPregnancy and ChildbirthPreterm birth

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pregnancies at increased risk of preterm birth
Sponsor
niversity of Toronto Faculty of Medicine Research Office (Canada)
Enrollment
1900
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
February 10, 2004
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
Female

Investigators

Sponsor
niversity of Toronto Faculty of Medicine Research Office (Canada)

Eligibility Criteria

Inclusion Criteria

  • •1\. Women who have previously received one completed course of ACS, 14 to 21 days ago, and continue to be at increased risk of preterm birth
  • •2\. Women of child\-bearing age; their children from birth to 24 months corrected gestational age, either sex
  • •3\. Gestational age more than or equal to 26 weeks of gestation and less than 30 completed weeks
  • •4\. Women at 25 to 32 weeks gestation who remain at increased risk of preterm birth 14 to 21 days after a single course of antenatal corticosteroids

Exclusion Criteria

  • •1\. Women requiring chronic doses of corticosteroids secondary to medical conditions
  • •2\. Women with a contraindication to corticoosteroids
  • •3\. Women with clinical evidence of chorioamnionitis (temperature more than or equal to 38°C)
  • •4\. Known lethal congenital anomaly (e.g. anencephaly) in any fetus
  • •5\. First course of ACS given prior to 23 weeks
  • •6\. Previous participation in MACS

Outcomes

Primary Outcomes

Not specified

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