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Clinical Trials/NCT04347785
NCT04347785
Recruiting
Not Applicable

Preoperative, Intraoperative and Postoperative Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia

Universidade do Porto1 site in 1 country206 target enrollmentJanuary 1, 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Carotid Endarterectomy
Sponsor
Universidade do Porto
Enrollment
206
Locations
1
Primary Endpoint
Stroke
Status
Recruiting
Last Updated
6 years ago

Overview

Brief Summary

Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established.

The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated.

Detailed Description

Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established. The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated. All consecutive patients from a tertiary referral center who underwent CEA for carotid artery stenosis (CS) and consecutive patients who presented alterations in the neurologic examination after ICA clamping during CEA are selected. The control patients, submitted to the same procedure but with no neurologic alterations, are consecutively selected.

Registry
clinicaltrials.gov
Start Date
January 1, 2011
End Date
December 31, 2030
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

João Rocha Neves

Consultant of Angiology and Vascular Surgery, MD/MSc, MPH epidemiology, FEBVS

Universidade do Porto

Eligibility Criteria

Inclusion Criteria

  • carotid endarterectomy under regional anesthesia
  • Postclamping carotid deficit

Exclusion Criteria

  • carotid stenting

Outcomes

Primary Outcomes

Stroke

Time Frame: up to 5 years

An episode of neurological dysfunction caused by focal cerebral, spinal, or retinal infarction.

Secondary Outcomes

  • Clavien-Dindo Classification >3(30 days)

Study Sites (1)

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