Preoperative, Intraoperative and Postoperative Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Carotid Endarterectomy
- Sponsor
- Universidade do Porto
- Enrollment
- 206
- Locations
- 1
- Primary Endpoint
- Stroke
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established.
The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated.
Detailed Description
Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established. The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated. All consecutive patients from a tertiary referral center who underwent CEA for carotid artery stenosis (CS) and consecutive patients who presented alterations in the neurologic examination after ICA clamping during CEA are selected. The control patients, submitted to the same procedure but with no neurologic alterations, are consecutively selected.
Investigators
João Rocha Neves
Consultant of Angiology and Vascular Surgery, MD/MSc, MPH epidemiology, FEBVS
Universidade do Porto
Eligibility Criteria
Inclusion Criteria
- •carotid endarterectomy under regional anesthesia
- •Postclamping carotid deficit
Exclusion Criteria
- •carotid stenting
Outcomes
Primary Outcomes
Stroke
Time Frame: up to 5 years
An episode of neurological dysfunction caused by focal cerebral, spinal, or retinal infarction.
Secondary Outcomes
- Clavien-Dindo Classification >3(30 days)