Comparison of the effect of coma induced by thiopental and propofol in Traumatic Brain Injury patients

Phase 2

• Conditions: Patients with traumatic brain injury.; Traumatic cerebral edema with loss of consciousness of any duration with death due to brain injury prior to regaining consciousness; S06.1X7

• Registration Number: IRCT20210415050976N1
• Lead Sponsor: Jahrom University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 May 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Satisfaction to participate in the study
Consciousness level less than 8 according to Glasgow Coma Scale (GCS)
Head injury without damage to other vital organs
Full consent of the patient and his / her legal guardians to participate in the study

Exclusion Criteria

pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Induction of coma. Timepoint: Before injection and then for three days (three times a day: morning, noon and night shifts). Method of measurement: By bispectral index criteria.

Secondary Outcome Measures

Name	Time	Method
evel of consciousness. Timepoint: Measure before injection and after injection daily (every 15 minutes) for 3 days. Method of measurement: Glasgow Criterion.;Vital signs. Timepoint: Measure before injection and after injection daily (every 15 minutes) for 3 days. Method of measurement: Monitoring device.