Bone Mineral Density in Patients With Sarcoidosis

Completed

• Conditions: Sarcoidosis; Osteoporosis Risk

• Registration Number: NCT06238037
• Lead Sponsor: University of Aarhus

Brief Summary

To assess the frequency and risk factors of decreased bone mineral density (BMD) and vertebral fractures in Danish patients with sarcoidosis.

Detailed Description

An increased risk of bone fracture has been found in patients with sarcoidosis. Some data showed that the risk of fracture was limited to patients treated with glucocorticoid but data are conflicting and not all studies can prove an increased risk of fracture or bone mineral loss in sarcoidosis.

Study Timeline

• Study Start: 2019-12-01
• Study First Submitted: 2022-06-03
• Study First Submitted QC: 2024-01-24
• Study First Posted: 2024-02-02
• Primary Completion: 2024-04-30
• Study Completion: 2024-04-30
• Status Verified: 2024-12
• Last Update Submitted: 2025-03-03
• Last Update Posted: 2025-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 144

Inclusion Criteria

• Diagnosis of sarcoidosis
• Signed informed consent

Exclusion Criteria

• Inability or unwillingness to adhere to the study
• Inability to give informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of patients with osteopenia	2 years from diagnosis	Mean BMD at 2 years and the distribution of osteopenia osteoporosis and normal scans
Number of patients with osteoporosis	2 years from diagnosis	Mean BMD at 2 years and the distribution of osteopenia osteoporosis and normal scans

Secondary Outcome Measures

Name	Time	Method
Number of participants with vertebral fracture	2 years from diagnosis	Proportion of patients with vertebral fracture

Trial Locations

Locations (1)

Aarhus University Hospital. Dep. of Respiatory Diseases and Allergology; 🇩🇰 Aarhus N, Denmark