A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
Recruiting
- Conditions
- Anesthesia
- Interventions
- Diagnostic Test: Echocardiography
- Registration Number
- NCT05954832
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Brief Summary
The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
- Adult patients ≥ 18 years of age requiring general anesthesia for surgery
- Intubation required for anesthetic management / surgery
- Anticipated prep time before incision of 20 minutes
- Baseline MAP >70mmHg
Exclusion Criteria
- History of coronary artery disease
- History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities)
- History of peripheral artery occlusive disease
- Beta-blocker use
- Anti-hypertensive medication use
- Patients with epidural, spinal, paravertebral, serratus blocks preoperatively
- Patients requiring rapid sequence induction (where intubation occurs concurrently with induction)
- Emergency surgery
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Echocardiography Echocardiography Patients participating in this study will undergo routine anesthetic and perioperative care with the addition of an echocardiography and Clearsight BP measurement.
- Primary Outcome Measures
Name Time Method The proportion of patients with post-induction hypotension (PIH) up to 20-mins after anesthesia induction. summarize the distributions of the echocardiography parameter values (pre-load LVEDd(cm), after-load LVEDs(cm), other measures \[e.g., contractility (EF %) and structural abnormalities\]) across each timepoint among patients with and without PIH
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Memorial Sloan Kettering Cancer Center (All protocol activites)
🇺🇸New York, New York, United States