The effect of appetite suppressant treatment on hunger and rebound eating in fasting wome

Not Applicable

• Conditions: Obesity; Diet and Nutrition - Obesity

• Registration Number: ACTRN12622000107729
• Lead Sponsor: The New Zealand Institute for Plant and Food Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-01-24
• Last Update Posted: 31 January 2022

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

Females
Aged 18-40 years
BMI 18.5-25kg/m2
Premenopausal
Normal gross gastrointestinal tract anatomy, as ascertained by self-report
Generally healthy, as ascertained by self-report
Regularly eat breakfast and lunch and dinner, as determined by self-reporting.
Regular menstrual cycle as ascertained by self-report

Exclusion Criteria

Any medical conditions or medications known to affect appetite -related parameters, including depression, diabetes and glucose intolerance or supplements that regulate appetite.
Participation in an active diet program and/or loss/gain of >10% body weight within the last 6 months
Smoker or ex-smoker who quit within the last 6 months
Hypersensitivities or allergies to any ingredients included in the study capsules
Dislike and/or unwilling to consume items listed as study foods
Unwilling/unable to comply with study protocol
Conditions effecting the gastrointestinal tract
Participating in another clinical intervention trial
Abnormal hunger and meal patterns, as ascertained by self-assessment
Any medical condition that may affect ability to safely participate in a 24h fast.
Frequently take part in fasting or intermittent fasting
Trying or likely to get pregnant
Likely or planning to either start or stop taking hormonal-based contraception during the trial.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in subjective measures of appetite as determined by Visual Analogue Scale (VAS) for Hunger[VAS measures will be taken through the 16h to 24h fasting period every 30 mins. Specifically at 1000h (t=0), 1030h, 1100h, 1130h, 1200h, 1230h, 1300h, 1330h 1400h, 1430h, 1500h, 1530h, 1600h, 1630h, 1700h, 1730h and 1800h (t=480)];Changes in subjective measures of appetite as determined by Visual Analogue Scale (VAS) for Fullness[VAS measures will be taken through the 16h to 24h fasting period every 30 mins. Specifically at 1000h (t=0), 1030h, 1100h, 1130h, 1200h, 1230h, 1300h, 1330h 1400h, 1430h, 1500h, 1530h, 1600h, 1630h, 1700h, 1730h and 1800h (t=480)];Changes in subjective measures of appetite as determined by Visual Analogue Scale (VAS) for Satisfaction<br>[VAS measures will be taken through the 16h to 24h fasting period every 30 mins. Specifically at 1000h (t=0), 1030h, 1100h, 1130h, 1200h, 1230h, 1300h, 1330h 1400h, 1430h, 1500h, 1530h, 1600h, 1630h, 1700h, 1730h and 1800h (t=480)]