MedPath

Effects of vibrating insoles on improving peripheral sensation in people with diabetic peripheral neuropathy

Phase 2
Completed
Conditions
Diabetic peripheral neuropathy due to type 2 diabetes
Nervous System Diseases
Registration Number
ISRCTN15526470
Lead Sponsor
Manchester Metropolitan University
Brief Summary

2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38536962/ (added 06/06/2024)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
22
Inclusion Criteria

1. Diagnosis of type 2 diabetes mellitus
2. Aged >18 years
3. Presence of at least one pedal pulse
4. Presence of moderate diabetic peripheral neuropathy defined by a vibration perception threshold > 15V
5. Ability to walk unaided for 30 steps
6. Able to understand all of the study requirements
7. Fit shoe size UK 8-12

Exclusion Criteria

1. Active foot ulcer
2. NHS prescription footwear
3. Lower limb amputation (anything more than amputation of two lesser toes)
4. Severe deformity due to Charcot Neuroarthropathy
5. Major foot deformities, including diabetes and non-diabetes-related deformities
6. Dementia or other cognitive impairment
7. Significant cardiopulmonary or other systemic disease limiting the patient’s ability to walk 30 steps
8. Person with bodyweight greater than 100kg (due to insole device limitations)
9. Use of a pacemaker
10. Inability to understand verbal and written information in English

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postural sway during standing, walking and stair negotiation are measured using a 3D motion capture system and force platforms before and after each vibration condition
Secondary Outcome Measures
NameTimeMethod
1. Gait kinematics and kinetics are measured using a 3D motion capture system and force platforms before and after each vibration condition<br>2. Muscle activation using surface electromyography (sEMG) before and after each vibration condition<br>
© Copyright 2025. All Rights Reserved by MedPath