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Clinical Trials/NCT04720872
NCT04720872
Completed
Not Applicable

Manual Therapy Combined With Physical Therapist-Directed Vestibular Rehabilitation in Patients With Unilateral Peripheral Vestibular Hypofunction: A Randomized Controlled Trial.

University of Jaén1 site in 1 country80 target enrollmentJanuary 20, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Peripheral Vestibular Disorder
Sponsor
University of Jaén
Enrollment
80
Locations
1
Primary Endpoint
Dizziness Handicap Inventory
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Randomized clinical trial with a control group that aims to evaluate the effects of a manual therapy protocol, together with a physical therapist-directed vestibular rehabilitation program, in patients with unilateral peripheral vestibular hypofunction. The intervention period will last approximately 4 weeks. Outcome measures will be collected at baseline, just after the intervention, as well as 1 and 6 months after the intervention.

Detailed Description

Peripheral vestibular disorders are common in otorhinolaryngology practice. These patients often complain of vertigo and dizziness, as well as balance problems, causing an important impact on health-related quality of life. The objective of this study was to investigate the effects of manual therapy combined with physical therapist-directed vestibular rehabilitation in patients with unilateral peripheral vestibular hypofunction. The design of this study is a randomized controlled trial with two groups (experimental and control groups). The impact of dizziness on daily function and quality of life (Dizziness Handicap Inventory), the fear of falling and the balance confidence (Activities-specific Balance Confidence scale-16 items), postural control (stabilometric platform) as well as the intensity (visual analogue scale) and number of the vertiginous crisis will be determined. The intervention period will last four weeks. Participants of the experimental group will receive 4 sessions of manual therapy together with physical therapist-directed vestibular rehabilitation, while participants of the control group will receive home-based vestibular rehabilitation. Outcome measurements will take place at baseline, immediately after the intervention, one month and six months after the intervention. Within-group and between-group data will be analyzed and interpreted.

Registry
clinicaltrials.gov
Start Date
January 20, 2021
End Date
January 31, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University of Jaén
Responsible Party
Principal Investigator
Principal Investigator

Agustín Aibar Almazán

Principal investigator

University of Jaén

Eligibility Criteria

Inclusion Criteria

  • Patients aged ≥ 18 years with a clinical diagnosis of unilateral peripheral vestibular hypofunction confirmed by Video Head Impulse Test (\< 0.8), referring balance impairments, postural instability, gait instability, vertigo, dizziness or motion sensitivity, able to understand and complete e instructions, programs, and protocols of this project, and providing a signed informed consent.

Exclusion Criteria

  • Central nervous system, degenerative or cancer diseases, acute infection.
  • Morphological/ functional alterations of the lower limbs, and/or morphological alteration of the cervical and/or suboccipital rachis.
  • Conditions (i.e. neuromuscular disease or traumatism) that contraindicate the performance of the exercises and interventions of this study, as well as cognitive impairment that prevents the participants from understanding and completing the questionnaires and interventions.
  • Positive results for the Klein test and the Rancurel test, or cerebrovascular alterations.

Outcomes

Primary Outcomes

Dizziness Handicap Inventory

Time Frame: Baseline-4 weeks

Evaluates the level of disability related to the impact of dizziness on daily function and quality of life.

Secondary Outcomes

  • ABC-16 (Activities-specific Balance Confidence scale-16 ítems)(Baseline-4 weeks)
  • STABILOMETRIC PLATFORM(Baseline-4 weeks)
  • Visual-Analogue-Scale (VAS)(Baseline-4 weeks)
  • The number of crisis(Baseline-4 weeks)

Study Sites (1)

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