3D Imaging: Prognostic Role in Pulmonary Arterial Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Number of death from any cause
研究概览
简要总结
Pulmonary hypertension is a rare and severe disease, affecting a young population. Survival is very poor and has been closely related to right ventricular dysfunction. Current prognostic equations rely mostly on right heart catheterization data. The identification of simple echocardiographic prognostic factor is urgently needed. It could help identifying with a non invasive method, high risk patients who could benefit from an intensive specific therapy. 3D right ventricular imaging is a new echocardiographic tool which provides RV volumic analysis, RV ejection fraction, overcoming the classical limits of 2D ultrasound.
The aim of this study is to validate a new software for 3D analysis of the right ventricle and assess its prognostic role in pulmonary hypertension.
To do so, the investigators will realize a prospective monocentric longitudinal cohort study, including 100 pulmonary hypertension patients. Echocardiographic data will be collected at baseline and after 6 months.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients > 18 years old
- •Pulmonary hypertension diagnosed by right heart catheterization
- •Informed consent obtained
- •Affiliation to the French national health insurance
排除标准
- •Associated significant left heart disease
- •Sub-optimal acoustic windows
- •Patient unable to attend follow-up visits
研究组 & 干预措施
Control
Echocardiographic data : 3D right ventricular Imaging on 50 patients without pulmonary hypertension only at baseline
干预措施: 3D right ventricular imaging echocardiographic (Device)
Case
Echocardiographic data : 3D right ventricular imaging on 100 pulmonary hypertension patients at Baseline and after six months
干预措施: 3D right ventricular imaging echocardiographic (Device)
结局指标
主要结局
Number of death from any cause
时间窗: Baseline to 24 months
Description of the number of death during the study
次要结局
- Number of Hospitalisation(Baseline to 24 months)
- 3D right ventricular imaging echocardiographic(Baseline and 6 months)