Study of the effect of surfactant in respiratory distress of preterm neonates
Phase 2
- Conditions
- Respiratory distress of newborn.Respiratory distress of newborn, unspecified
- Registration Number
- IRCT2014080716937N4
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
preterm neonates with 34 week age or less; respiratory distress due to surfactant deficiency;
Exclusion criteria: parents have not consent with incorporating in study; neonate with asphyxia; neonates with intubation from the birth; respiratory distress not due to RDS; neonates with maternal abnormality
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eed for second dose surfactant. Timepoint: Per 6 hour after intervention. Method of measurement: Chart.;Apnea. Timepoint: During hospitalization. Method of measurement: Visit.;Duration of Oxygen Consumption. Timepoint: Per 6 hour after intervention. Method of measurement: Chart.
- Secondary Outcome Measures
Name Time Method Complications of surfactant injection (Coughing or Gagging, Pneumothorax, Surfactant Reflux, Bradycardia, Pulmonary Hemorrhage, Intra ventricular Hemorrhage (>grade 2)). Timepoint: Per 6 hour after intervention. Method of measurement: Chart and visit.;The rate of intubated in First 72 h of Life. Timepoint: Per 6 hour after intervention. Method of measurement: Chart.;Length of Stay in NICU. Timepoint: Per 6 hour after intervention. Method of measurement: Chart.;Death. Timepoint: During hospitalization. Method of measurement: Chart.