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临床试验/NCT03344224
NCT03344224已完成不适用

The Relationship of Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event Occurence

Peking University First Hospital0 个研究点目标入组 50,000 人开始时间: 2017年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
50,000
主要终点
cardiovascular events

研究概览

简要总结

Whether the pre-operative blood lipid level and post-operative cardiovascular events is associated is unknown. This study is to find out the main blood lipid and relative protein level change and the post-operative cardiovascular events occurrence.

详细描述

The participants collected data from their hospital.Patients under going non-cardiac surgery were collected. Data of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were collected perioperatively. The postoperative major cardiovascular and cerebral events were also identified and collected. Other data including perioperative information and surgeries and anesthesia data were gathered.

Logistic regression models were built and selected. Independent risk factors relative to postoperative major cardiovascular and cerebral events were screened and identified. different levels of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were analysed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • non-cardiac surgery patients with preoperative blood lipid tests

排除标准

  • electronic records missing or peri-operative data missing

结局指标

主要结局

cardiovascular events

时间窗: 30 days postoperatively

such as acute myocardial infarction

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yan Zhou, MD

Principal Investigator,

Peking University First Hospital

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