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Clinical Trials/NCT06263634
NCT06263634
Completed
Not Applicable

Investigation of the Effect of Hand Exercises on Grip Strength, Functionality, Disease Activity and Quality of Life in Patients With Psoriatic Arthritis

Akdeniz University1 site in 1 country34 target enrollmentStarted: April 5, 2023Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
34
Locations
1
Primary Endpoint
Psoriatic Arthritis Disease Activity Score (DAPSA)

Overview

Brief Summary

This study is a randomized controlled study examining the effects of 8-week hand home exercises on grip strength, functionality, disease activity and quality of life in patients with PsA. Individuals participating in the study will be randomly divided into 2 groups. Individuals in the intervention group will perform home exercises consisting of stretching, mobility and strengthening, 4 days a week for 8 weeks, and the patients' compliance with the exercise will be monitored by phone call once a week. Individuals in the control group are on the waiting list and the same home exercise program will be taught to the patients at the end of the study.

Detailed Description

Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease that is in the spondyloarthritis group and is frequently accompanied by peripheral arthritis, dactylitis, enthesitis, spondylitis and accompanied by psoriasis. Although hand effects in patients with PsA are known, there is no exercise study performed only on the hand and no study examining the effect of this study on the grip strength and functionality of the hand. This study is a randomized controlled study examining the effects of 8-week hand home exercises on grip strength, functionality, disease activity and quality of life in patients with PsA. 34 individuals with PsA who meet the inclusion criteria will be included in the study. Individuals participating in the study will be randomly divided into 2 groups. Individuals in the intervention group will perform 30-45 minutes of home exercises consisting of stretching, mobility and strengthening, 4 days a week for 8 weeks, and the patients' compliance with the exercise will be monitored by phone call once a week. Individuals in the control group are on the waiting list and the same home exercise program will be taught to the patients at the end of the study. Evaluations will be made twice, at the beginning and at the end of the 8-week program. In the evaluation, the demographic form, Psoriatic Arthritis Disease Activity Score (DAPSA), Grip Strength, Nine-Hole Peg Test, Duruöz Hand Index, Michigan Hand Outcome Questionnaire (MHQ) Functional Hand Index, Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL) will be applied. This study will be one of the first studies to show the effects of hand exercises on PsA disease activity, grip strength, functionality and quality of life.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Being diagnosed with PsA by a physician according to CASPAR criteria
  • Being 18 years or older
  • Involvement in hand joints (pain, swelling, tenderness)
  • Being on stable drug treatment for the last 6 months
  • Having sufficient cooperation to participate in the study
  • Volunteering to participate in the study

Exclusion Criteria

  • Having difficulty cooperating at work
  • Having additional orthopedic and/or neurological disease that will affect hand functions

Outcomes

Primary Outcomes

Psoriatic Arthritis Disease Activity Score (DAPSA)

Time Frame: 8 weeks

DAPSA; It is a composite measurement focused on peripheral arthritis, developed for reactive arthritis, adapted to PsA patients and frequently used, evaluating disease activity and response to treatment in clinical studies. There are four components of score including the parameters a) tender joint count (68 joints), b) swollen joint count (66 joints), c) CRP value (mg/l) and d) patient's disease activity and pain assessment (with a 10 cm visual analog scale). DAPSA scores are calculated by summing each of these components. Cut-off values for disease activity; A score of \<4 was determined as remission, a score of \<14 was determined as minimal disease activity, a score of \<28 was determined as moderate disease activity, and a score of 28 was determined as high degree of disease activity.

Hand grip strength measurement

Time Frame: 8 weeks

Hand grip strength will be measured with a Jamar hydraulic hand dynamometer (Sammons Preston, USA). Grip tests will be performed in the standard position recommended by the American Association of Hand Therapists. This is the standard position; The patient is seated in a position that provides 90-20 degree flexion of the hip and knee, shoulder adduction, forearm neutral position, 90 degree flexion of the elbow, 0-30 degree extension of the wrist and 0-15 degree ulnar deviation. The measurement will be repeated three times. There will be a 15-second rest break at the end of each measurement. As a result, the average of three measurements will be recorded.

Hand fine grip strength measurement:

Time Frame: 8 weeks

Fine grip strength measurements will be made with finger dynamometry (Pinchmeter-Sammons Preston, USA). Grip tests will be performed in the standard position recommended by the American Association of Hand Therapists. This is the standard position; The patient is seated in a position that provides 90 degrees of hip and knee flexion, shoulder adduction, forearm neutral position, 90 degree flexion of the elbow, 0-30 degree extension of the wrist and 0-15 degree ulnar deviation. Three different finger grips will be evaluated. These: 1- Fingertip grip strength, 2- Lateral grip strength, 3- Three point grip strength. Measurements will be repeated three times. There will be a 15-second rest break at the end of each measurement. As a result, the average of three measurements will be recorded.

Secondary Outcomes

  • Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL)(8 weeks)
  • Nine-Hole Peg Test(8 weeks)
  • Duruöz Hand Index(8 weeks)
  • Michigan Hand Outcome Questionnaire (MHQ)(8 weeks)
  • Hand Functional Index (HFI)(8 weeks)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Sebahat Yaprak Cetin, PT

Principal Investigator

Akdeniz University

Study Sites (1)

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