Refractive and Corneal Topographic Characteristics in Upper Egypt Children With High Cylinder

Completed

• Conditions: Corneal Ectasia
• Interventions: Other: Pentacam and autorefractometry

• Registration Number: NCT06348368
• Lead Sponsor: Sohag University

Brief Summary

Refractive and Corneal Topographic Characteristics in upper Egypt children with high cylinder: A cross sectional study

Detailed Description

Astigmatism is defined as, a refractive condition in which refractive light fails to form a focus on the retina, it accounts for about 13% of refractive errors. It is frequent and correctable cause of visual impairment in children whether associated with spherical errors or not.

Astigmatism, is the refractive error of the highest clinical importance, being associated with reduced visual acuity with subsequent development of refractive amblyopia.

High cylinder in children belong to areas of hot and dry climates, makes exclusion of keratoconus is mandatory. Population in the African continent, the Mediterranean countries, Central and South America, and the Indian subcontinent usually have the habit of eye rubbing because of bothering symptoms of dryness, itching, atopy, allergy and vernal keratoconjunctivitis, which is the severe form of allergic conjunctivitis.

Eye rubbing causes thinning of keratocyte and increases the prevalence of keratoconus.

Keratoconus in children (diagnosed before the age of eighteenth) is less common but more aggressive than that of the adults, due to the dynamic nature of the young cornea. Few studies in the literature reported the prevalence and incidence of keratoconus in children.

Pentacam is an advanced instrument with a rotating Scheimpflug camera for scanning the anterior and posterior corneal surfaces. Its measurements of the corneal thickness and posterior elevation have been proved to be of high reproducibility and repeatability.

Study Timeline

• Study Start: 2023-01-01
• Primary Completion: 2024-01-30
• Study Completion: 2024-02-01
• Study First Submitted: 2024-03-27
• Study First Submitted QC: 2024-03-30
• Status Verified: 2024-04
• Study First Posted: 2024-04-04
• Last Update Submitted: 2024-04-06
• Last Update Posted: 2024-04-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4000

Inclusion Criteria

• Upper Egypt children with high cylinder(refractive errorr).

Exclusion Criteria

• Children below age of 7 years old (uncooperative), patients above age of 18 years old.Patients with corneal scars

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1 (control group)	Pentacam and autorefractometry	Children with normal Pentacam and with no refractive errors
Group 3 (Children with high cylinder and corneal ectatic changes).	Pentacam and autorefractometry	Children with high cylinder and corneal ectatic changes
Group 2 (children with high cylinder and no corneal topographic abnormalities)	Pentacam and autorefractometry	Children with high cylinder without corneal topographic ectasia.

Primary Outcome Measures

Name	Time	Method
Values anterior and posterior corneal elevation values by pentacam.	one year	Corneal topgraphic changes in children with high cylinder in upper Egypt

Trial Locations

Locations (1)

Elshimaa A.Mateen; 🇪🇬 Sohag, Egypt