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Efficacy of Oral Disintegrating Strip Sildenafil for the Treatment of Erectile Dysfunction: A Prospective, Randomized Trial

Phase 2
Conditions
Erectile dysfunction
Registration Number
TCTR20180216002
Lead Sponsor
The Government Pharmaceutical Organization
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
Male
Target Recruitment
120
Inclusion Criteria

- Patients with erectile dysfunction condition who are ≥ 18 years old.
- Sexual intercourse is failed for ≥ 50% of total sexual activities
- Erectile dysfunction for ≥ 3 months
- Have only one heterosexual partner and have sexual intercourse at least 2 times per month
- Agree to participate in this study and sign the informed consent form

Exclusion Criteria

- Any history of contraindication or hypersensitivity to PDE5 inhibitors
- Any history of insensitive to PDE5 inhibitor treatment
- Erectile dysfunction due to spinal cord injury
- History of radical prostatectomy
- Having untreated blood glucose > 270 mg/dl
- Having untreated hypogonadism
- PSA > 4 ng/dl
- Presence of abnormal condition in cardiovascular, hepatic, and renal systems which might be compromised by PDE5 inhibitor treatment
- Presence of orthostatic hypotension or uncontrolled blood pressure

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
IIEF-5 and EHS scores Screening, Enrollment, 4 weeks and 8 weeks post dose, and end of study Questionaires
Secondary Outcome Measures
NameTimeMethod
Safety Screening, Enrollment, 4 weeks and 8 weeks post dose, and end of study Vital signs and laboratory measurements
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