Diabetic Peripheral Neuropathy: Correlation Between Ultrasound Findings and Clinical Features
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 106
- 主要终点
- Pain scores on the visual analog scale
研究概览
简要总结
The current study aimed to evaluate the cross-sectional area (CSA) of peripheral nerves in people with diabetic peripheral neuropathy using ultrasonography and correlate the CSA with clinical and demographic data.
详细描述
Patients with diabetic peripheral neuropathy (n=53) and a matched healthy control group (n=53) underwent blinded ultrasonography imaging of the sciatic, tibial and median nerves. Matching was performed according to patient body mass index (BMI), sex and age. CSAs of the nerves were recorded, and the associations between pain intensity (measured with a visual analog scale [VAS]), the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale, diabetes mellitus duration, BMI, HbA1c and blood glucose levels were evaluated.
研究设计
- 研究类型
- Observational
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •type 2 diabetes mellitus
- •Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scores ≥ 12
- •probable diabetic peripheral neuropathy according to the diabetic peripheral neuropathy criteria.
- •Exclusion Criteria
- •type 1 diabetes mellitus
- •hypothyroidism
- •LANSS pain scale scores < 12
- •body mass index (BMI) > 35
- •current pregnancy
- •histories of hereditary neuropathy, inflammatory neuropathy, nerve trauma, or other known causes of polyneuropathy; and the use of anti-neuropathic drugs.
排除标准
- 未提供
结局指标
主要结局
Pain scores on the visual analog scale
时间窗: 3 years
次要结局
- Neuropathic pain scores on the Leeds Assessment of Neuropathic Symptoms and Signs pain scale(3 years)
研究者
Bayram Kelle
Director
Cukurova University