Risk Factors for Benign Breast Disease in Young Adult Women. Case-control Study
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Relative risk of benign breast disease associated with soda beverage consumption.
研究概览
简要总结
Benign diseases of the breast are common clinical conditions that affect young women. Complaints related to the breast often cause significant discomfort and mental stress. The following study will try to identify the risk factors that may be associated with symptomatic benign breast diseases. Identification of such factors may help preventing and / or treating these conditions.
详细描述
Benign breast disease (BBD) is a common cause of hospital visit. In young adults, benign breast conditions surpass cancer as a cause of symptoms related to the breast. However, breast symptoms may be associated with significant distress and may impose diagnostic difficulties. Moreover, certain pathological entities of benign breast conditions are well known to increase the risk of breast cancer.
Identification of modifiable risk factors associated with symptomatic breast disorders has several potential benefits. Modification of such factors may help decrease patients' distress, hospital visits and indirectly decrease the risk of cancer.
the available data point to the possible association of several environmental factors with symptomatic BBD. Most of the available information points to an association of BBD with anthropometric features, growth pattern, family history of breast conditions and dietary consumption. Substantial evidence are however lacking and further studies are strongly required to better characterize the risk factors of the condition.
In this study, the investigators will systematically collect epidemiological, developmental and clinical data in young patients presenting with breast complaints. The association with disease incidence, pattern and histology will be examined.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •adult females with current symptoms related to the breast.
排除标准
- •Current or past malignancy of the breast.
- •Discrete breast mass that necessitate work-up to exclude cancer.
- •Current psychiatric morbidity.
- •Persons unwilling to participate.
结局指标
主要结局
Relative risk of benign breast disease associated with soda beverage consumption.
时间窗: This outcome will be assessed at baseline (the first hospital visit).
for the study and control groups, the participant will be asked about soda beverage consumption in the last 30 days. never consumed is scored 0 (lowest score). Three or more times a day is scored 9 (highest score).
Relative risk of benign breast disease associated with caffeine beverages consumption.
时间窗: This outcome will be assessed at baseline (the first hospital visit).
for the study and control groups, the participant will be asked about caffeine beverage consumption in the last 30 days. never consumed is scored 0 (lowest score). Three or more times a day is scored 9 (highest score).
Relative risk of benign breast disease associated with parity.
时间窗: This outcome will be assessed at baseline (the first hospital visit).
for the study and control groups, the participant will be asked about her parity. response will be either nullipara, primipara, multipara or grand multipara ( 5 or more births).
Relative risk of benign breast disease associated with obesity.
时间窗: This outcome will be assessed at baseline (the first hospital visit).
For the study and control groups, body mass index will be calculated as the weight (Kg) to square height (m) ratio.
次要结局
未报告次要终点
研究者
Osama Hussein
Professor of Surgery
Mansoura University