Aerobic Exercises Versus Laser Puncture Therapy on Immune Response Following Neck Lymph Node Dissection
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Cairo University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Leukocyte total count and differential lymphocyte count measurements
Study Overview
Brief Summary
Group (1): Twenty cases with decreased white blood cell counts after neck lymph nodes and deficient in blood immunological functions made up this group. They underwent aerobic exercise training on a cycle ergometer. The cases received one 15-minute session, three sessions per week, for two months, with follow-up after the course of treatment.
Group (2): Twenty cases with underdeveloped blood immune systems; decreased white blood cell counts after having their neck lymph nodes removed, a low-level laser puncture was performed on the Governing Vessel 14 acupuncture point. They received a 15-minute session, three sessions per week, for two months, with follow-up after the course of treatment
Detailed Description
Inclusion criteria:
All cases were checked carefully by a physician before the study procedures. All cases were approximately the same age. All cases were conscious. All cases in both groups obtained the same medications and they received three sessions per week for 2 months. All patients enrolled in the study had a deficiency in blood immune functions post neck lymph node dissection and received chemotherapy.
Exclusion criteria:
Patients with associated disease (other pathological conditions), patients suffering from metastases, patients taking medications that alter leukocytes count and pregnancy or epilepsy.
Measurement procedures:
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 40 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All cases were checked carefully by a physician before the study procedures. All cases were approximately the same age.
- •All cases were conscious. All cases in both groups obtained the same medications and they received three sessions per week for 2 months.
- •All patients enrolled in the study had a deficiency in blood immune functions post neck lymph node dissection and received chemotherapy.
Exclusion Criteria
- •Patients with associated disease (other pathological conditions). patients suffering from metastases. patients taking medications that alter leukocytes count and pregnancy or epilepsy.
Arms & Interventions
Cycle ergometer treatment protocol (Group 1):
Twenty cases with decreased white blood cell counts after neck lymph nodes and deficient in blood immunological functions made up this group. They underwent aerobic exercise training on a cycle ergometer. The cases received one 15-minute session, three sessions per week, for two months, with follow-up after the course of treatment
Intervention: Cycle ergometer (Device)
Low-level laser treatment protocol (Group 2):
Twenty cases with underdeveloped blood immune systems; decreased white blood cell counts after having their neck lymph nodes removed, a low-level laser puncture was performed on the Governing Vessel 14 acupuncture point. They received a 15-minute session, three sessions per week, for two months, with follow-up after the course of treatment
Intervention: Low-level laser therapy (Device)
Outcomes
Primary Outcomes
Leukocyte total count and differential lymphocyte count measurements
Time Frame: 2 months
Measurement of immune response: The cases were seated when immune response was measured. Morning peripheral blood sample aspiration was followed by venous blood collection into sterile glass containers with the necessary anticoagulants and preservatives. A Coulter hematology analyzer (Coulter Electronics, USA) was used to perform differential counts of lymphocytes and the total leukocyte count.
Secondary Outcomes
No secondary outcomes reported
Investigators
Aya Gamal Fawzy El-Sayed
Doctor
Cairo University