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Clinical Trials/NCT06569693
NCT06569693
Recruiting
Not Applicable

Dyadic Sleep Study

University of Miami2 sites in 1 country152 target enrollmentOctober 22, 2024

Overview

Phase
Not Applicable
Intervention
My Sleep Our Sleep (MSOS) Program
Conditions
Gastrointestinal Cancer
Sponsor
University of Miami
Enrollment
152
Locations
2
Primary Endpoint
Change in sleep disturbance symptoms as measured by scores on the Pittsburgh Sleep Quality Index (PSQI)
Status
Recruiting
Last Updated
last month

Overview

Brief Summary

The purpose of this study is to learn about sleep behaviors and test different ways to help patients with cancer and caregiver partners.

Registry
clinicaltrials.gov
Start Date
October 22, 2024
End Date
December 1, 2026
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Youngmee Kim

Professor

University of Miami

Eligibility Criteria

Inclusion Criteria

  • The eligibility criteria for patients are:
  • newly diagnosed with stage I to IV of a GI cancer (anus, colon, esophagus, gallbladder, large and small intestine, liver, pancreas, rectum, stomach, other biliary or digestive organs)
  • diagnosis in the past 72 months at the time of enrollment
  • having a consistent sleep partner.
  • The eligibility criterion for caregivers is:
  • a sleep partner of the patient or partner who wish to resume sleeping together with the patient
  • Additional eligibility criteria for both patients and caregivers are:
  • Pittsburgh Sleep Quality Index (PSQI) ≥ 5,
  • willing to change sub-optimal sleep habits,
  • 18 years or older,

Exclusion Criteria

  • Exclusion criteria for both patients and caregivers are having had a diagnosis of major depressive disorder, psychosis, or bipolar disorder that is not currently treated;
  • Active suicidality, or substance or alcohol dependency in the past year;
  • Currently have narcolepsy, restless leg syndrome, or untreated sleep apnea that is screened using the Sleep Health Screen;
  • Both patients and caregivers have an extreme chronotype, or do shift work to have no overlap in sleep schedule between them; and plan trans-meridian travel during the period of data collection blocks; and having hearing or visual impairment, dementia, or cognitive dysfunction.
  • Adults unable to consent, individuals who are not yet adults, pregnant women, or prisoners will be excluded.

Arms & Interventions

MSOS Intervention Group

Participants (patient-sleep-partner caregiver dyads) in this group will receive the My Sleep Our Sleep (MSOS) intervention. Total participation is up to 13 weeks.

Intervention: My Sleep Our Sleep (MSOS) Program

BBTI Intervention Group

Participants (patient-sleep-partner caregiver dyads) in this group will receive the Brief Behavioral Treatment for Insomnia (BBTI). Total participation is up to 13 weeks.

Intervention: Brief Behavioral Treatment for Insomnia (BBTI)

Outcomes

Primary Outcomes

Change in sleep disturbance symptoms as measured by scores on the Pittsburgh Sleep Quality Index (PSQI)

Time Frame: Baseline, Up to 13 weeks

Change in sleep disturbance symptoms (patient-sleep-partner caregiver dyads) among participants will be compared and reported for both intervention groups, BBTI and MSOS, as measured by scores on the Pittsburgh Sleep Quality Index (PSQI). The PSQI is a self-reported, 19-item questionnaire health-related quality of life (HRQOL) questionnaire which assesses sleep quality and disturbances at baseline, week 5 and week 13. Questions generate seven "component" scores: subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medication, and daytime dysfunction. The sum of scores for these seven components yields one global score. A decrease of ≥ 5 points on the PSQI) will be considered as clinical improvement of symptoms.

Secondary Outcomes

  • Change in insomnia symptoms as measured by scores on the Insomnia Severity Index (ISI)(Baseline, Up to 13 weeks)

Study Sites (2)

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