The effect of ginseng in the treatment of brucellosis
Phase 3
- Conditions
- Brucellosis.Brucellosis
- Registration Number
- IRCT201412219855N8
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 165
Inclusion Criteria
age over 15 years; Wright titer at least 1/160 and 2ME 1/40; informed consent to participate in the study
Exclusion criteria: history of brucellosis in the past 2 years; history of chronic brucellosis; pregnant women; having innate or acquired immunodeficiency; history of allergy to ginseng; local forms of brucellosis infection such as endocarditis, spondylitis, etc.; patients with advanced or chronic disease of heart, lung, liver and kidney
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Disappearance of fever. Timepoint: Days of 0, 3, 5, 7, 14, 21. Method of measurement: With thermometer.;Resolve of arthralgia. Timepoint: Days of 0, 3, 5, 7, 14, 21. Method of measurement: Questionnaire.;Constitutional symptoms. Timepoint: Days of 0, 3, 5, 7, 14, 21. Method of measurement: Questionnaire.;Decrease of CRP. Timepoint: Days of 0,7, 14, 21, 28, 42. Method of measurement: Latex agglutination test.
- Secondary Outcome Measures
Name Time Method Treatment Failure. Timepoint: End of 6 weeks treatment. Method of measurement: No improvement in clinical symptoms and laboratory tests.;Relapse. Timepoint: Months of 3, 4, 5, 6, 7, 8. Method of measurement: ecurrence of clinical symptoms and laboratory tests.