Effect of supplemental oxygen by nasal cannula in 20 degree head up posiition during apnea interval of intubation- a prospective randomized double blind trial.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- 2. Increase in arterial oxygen due to supplemental oxygen insufflation
研究概览
简要总结
This study is a randomized, double blind, parallelgroup, trial assessing the effectiveness of supplemental oxygen nasal insufflation during apneic period of laryngoscopy as compared to no oxygen insufflation. The primary outcome measures will be assessing increase in desaturation safety period when arterial saturation comes down to 92% and also to assess effect on partial pressure of oxygen in arterial blood after intubation of this insufflation . The secondary outcomes willbe compare the recovery time for oxygen saturation to reach 100% after initiation of positive pressure ventilation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 15.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients ASA: Grade 1 Body mass index <25 kg/m2.
排除标准
- •Any lung pathology or respiratory problem Pregnant patients Anaemia modified mallampatti score >3 and/or anticipated difficult airway history of smoking in the last one week.
- •Any contraindication for nasal prong use eg tumors, fractures, trauma.
结局指标
主要结局
2. Increase in arterial oxygen due to supplemental oxygen insufflation
时间窗: 8 minutes | 5 minutes
1. Prolongation of time for saturation to come from 100% to 92% during laryngoscopy
时间窗: 8 minutes | 5 minutes
次要结局
- Saturation recovery time to 100 %, after positive pressure ventilation with 100% oxygen(9 minutes)