Phase 1/2 clinical trial to evaluate the safety and efficacy of daily intravitreal injections of KUS121 for three days in patients with non-arteritic central retinal artery occlusion - Phase 1/2 clinical trial of intravitreal injections of KUS121 in patients with central retinal artery occlusion

Kyoto University Hospital Institute for Advancement of Clinical and Translational Science0 sites9 target enrollmentSeptember 15, 2016

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: non-arteritic central retinal artery occlusion
Sponsor: Kyoto University Hospital Institute for Advancement of Clinical and Translational Science
Enrollment: 9
Status: Completed
Last Updated: 2 years ago

No summary available.

Registry

who.int

Start Date

September 15, 2016

End Date

March 20, 2018

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Kyoto University Hospital Institute for Advancement of Clinical and Translational Science

•1\) Patients who reported one or more of the following conditions: severe complications from cardiac, hepatic, or renal disease; poorly controlled diabetes mellitus 2\) Eyes with the following conditions: Acute ocular or periocular infection Uncontrolled intra ocular pressure despite medication Retinal venous occlusion Abnormality in the macula Opacity in the lens or the vitreous such that the fundus is not visible 3\) Contralateral eye: BCVA \<\= 0\.1, or visual field loss \>\= 1/2 of isopter I4e 4\) Bilateral onset of CRAO 5\) Systemic use of immunosuppressant or steroid medications 6\) Participation in other studies during the period 16 weeks prior 7\) Possibility or history of hypersensitivity reaction to fluorescein. 8\) Inability to understand consent requirements, or unwillingness or inability to participate in all of the follow\-up examinations 9\) Decision by the principal investigator or the physician in charge that patient was unsuitable for participation in the present study