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Clinical Trials/ISRCTN11966080
ISRCTN11966080
Completed
未知

A multicentre, double blind, placebo controlled, randomised trial to evaluate the effectiveness of a 1-day versus 7-day regimen of nitrofurantoin for the treatment of asymptomatic bacteriuria in pregnancy

World Health Organization (WHO) (Switzerland)0 sites778 target enrollmentDecember 14, 2007
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ConditionsAsymptomatic Bacteriuria (ASB)Infections and InfestationsBacteriuria

Overview

Phase
未知
Intervention
Not specified
Conditions
Asymptomatic Bacteriuria (ASB)
Sponsor
World Health Organization (WHO) (Switzerland)
Enrollment
778
Status
Completed
Last Updated
5 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2009 results in https://pubmed.ncbi.nlm.nih.gov/19155904/ (added 30/12/2020)

Registry
who.int
Start Date
December 14, 2007
End Date
March 1, 2007
Last Updated
5 years ago
Study Type
Interventional
Sex
Female

Investigators

Sponsor
World Health Organization (WHO) (Switzerland)

Eligibility Criteria

Inclusion Criteria

  • •1\. Pregnant women with gestational age 12 \- 32 weeks
  • •2\. Willing and able to give consent

Exclusion Criteria

  • •1\. Have any underlying disease, which require continuous steroid and/or antibiotic treatment, e.g. systemic lupus erythematosus, valvular heart disease, etc.
  • •2\. Use of any antibiotics during the past one\-week
  • •3\. Received any treatment for urinary tract infection at any time during the current pregnancy
  • •4\. History of nitrofurantoin hypersensitivity
  • •5\. Plan not to deliver at the study hospital
  • •6\. Any symptoms such as flank pain, dysuria that suggests symptomatic Urinary Tract Infections (UTI)
  • •7\. Have any haematological disease including Glucose\-6\-Phosphate Dehydrogenase deficiency (G6PD)
  • •8\. Negative urine dipslide
  • •9\. Negative urine culture
  • •10\. Positive urine culture but the organism is resistant to Nitrofurantoin

Outcomes

Primary Outcomes

Not specified

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