Breakdown, Identification and Observation of the microenvironment of acute and chronic wounds
Recruiting
- Conditions
- acute woundschronic wounds
- Registration Number
- DRKS00017390
- Lead Sponsor
- Institut für Translationale Wundforschung, Zentrum für biomedizinische Ausbildung und Forschung (ZBAF), Universität Witten/Herdecke
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 160
Inclusion Criteria
1. Men and women, aged 18 years or older
2. Signed informed consent
3. Existing wound for longer than 8 weeks ('chronic')
OR
4. Existing wound for over 24 hours and less than 6 days after traumatic event or surgical intervention ('acute')
Exclusion Criteria
1. Dry necrosis, dry wound bed, no wound bed sampling possible
2. Aged < 18 years
3. Pregnancy or nursing period
4. Wound of malignant entity (e.g. exulcerating tumor)
5. Non written consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Goal criterion: Acquisition of biological material for biomolecular analysis of chronic wound entities compared to acute wounds for correlation with healing phase and progression.<br><br>Sampling endpoint is marked by complete wound closure/epithelization making further wound bed swabbing impossible.
- Secondary Outcome Measures
Name Time Method