The WinFood Intervention Study: the effects of improved complementary foods on nutrition and health among Cambodian infants and childre
Not Applicable
Completed
- Conditions
- Infants at risk of undernutritionNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN19918531
- Lead Sponsor
- niversity of Copenhagen (Denmark)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 440
Inclusion Criteria
Children who are 6 months old and have a weight-for-height z-score > -3
Exclusion Criteria
1. Weight-for-height z-score < -3
2. Bilateral pitting oedema
3. Haemoglobin (Hb) < 80 g/L
4. Clinical signs of vitamin A deficiency (xerosis or Bitot spots). These children will be referred for treatment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in fat-free body mass (deuterium dilution) and iron status (serum ferritin and transferrin receptors) from baseline (age 6 months) until the end of the 9 month intervention
- Secondary Outcome Measures
Name Time Method Changes in:<br>1. Ponderal and linear growth<br>2. Physical activity (using an accelerometer, actigraph)<br>3. Motor milestones (questionnaire, clinic visits)<br>4. Morbidity<br>5. Haemoglobin concentration (using Haemocue)<br>6. Serum concentrations of acute phase proteins [C-reactive protein (CRP) and a-acid glycoprotein(AGP)], insulin-like growth factor (IGF)-1 and zinc<br>7. Whole blood fatty acid composition<br><br>Measured from baseline (age 6 months) until the end of the 9 month intervention