Effectiveness of an Intervention on Improving Medication Adherence in Pregnant Women with Anaemia: A Single-Blind Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
研究概览
简要总结
This single-blind randomized controlled trial evaluated the effectiveness of a combined educational and behavioural intervention on medication adherence among 98 pregnant women with moderate anaemia (Hb 7.0–10.9 g/dL) at 24–32 weeks of gestation. Participants were randomized into an intervention group receiving structured counselling on anaemia and iron therapy along with daily WhatsApp reminders, or a control group receiving routine iron therapy alone.
The primary outcome was change in medication adherence measured using the MMAS-8 scale. The intervention group showed a significant improvement in adherence scores (5.18 ± 0.8 to 7.91 ± 0.6; p<0.001), compared to modest improvement in the control group (5.08 ± 0.7 to 7.01 ± 0.6; p<0.05). Post-intervention adherence was significantly higher in the intervention group. Although hemoglobin levels improved more in the intervention group, the difference between groups was not statistically significant.
The findings suggest that combining structured education with digital behavioural reminders effectively enhances adherence to iron supplementation during pregnancy. Integrating such low-cost and scalable interventions into routine antenatal care may improve maternal health outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •Pregnant women between 13 and 24 gestational weeks, Age between 20 and 40 years Hemoglobin level at recruitment of 7.0 to 10.9 g/dL Recent onset as well as already on medication Who could read and write in Tamil or English, and had access to a smartphone with WhatsApp.
排除标准
- •Pregnant women were excluded if they had underlying diseases such as hemoglobinopathy(thalassemia, hemoglobin E), Chronic Diseases(cancer, chronic renal disease)or infectious disease (HIV, Malaria) Symptoms of anemmia (shortness of breath, chest pain, syncope) in current pregnancy.
研究者
Mridula Murali Manohar
SRM Medical College Hospital And Research Centre