NL-OMON53601
Not Yet Recruiting
N/A
High Flow Nasal Oxygen Therapy re-evaluated from a conceptual point of view: Effect on Respiratory Effort and Lung Aeration after Extubation - T-REX: Effect of HFNO Therapy on Respiratory Effort after Extubation
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 54
- Status
- Not Yet Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Aged \>\= 18 years
- •\- Receiving invasive mechanical ventilation \>48 hours for any cause
- •\- Scheduled for extubation as per local clinical guideline
- •\- Provided informed consent
Exclusion Criteria
- •\- Any clinical situation preventing appropriate execution of study procedures,
- •o Severe agitated delirium
- •o Do not reintubate order
- •\- The presence of a tracheostomy
- •\- Respiratory acidosis, defined as a pH \<7\.32 with hypercapnia (PCO2 \>6\.5 kPa /
- •PCO2 \> 50 mmHg) during or after SBT
- •\- Any feature that prohibits HFNO\-initiation
- •o Recent facial upper\-airway surgery
- •o Anatomic abnormalities that preclude appropriate fitting of HFNO
- •o Current exacerbation of obstructive pulmonary disease
Outcomes
Primary Outcomes
Not specified
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