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Clinical Trials/CTRI/2025/02/080774
CTRI/2025/02/080774
Not yet recruiting
Not Applicable

Comparison of Selective Trunk Block and Corner Pocket Approach of Supraclavicular Brachial Plexus Block : A Prospective Randomized Controlled Trial

Arshad Ayub1 site in 1 country50 target enrollmentStarted: March 1, 2025Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Arshad Ayub
Enrollment
50
Locations
1
Primary Endpoint
Comparison of sensory blockade of median, radial, ulnar and musculocutaneous nerves in both groups

Overview

Brief Summary

Supraclavicular brachial plexus block (BPB) is the most used regional anesthesia technique in upper limb surgeries. It is considered equivalent to spinal anesthesia in these surgeries due to its rapid onset, reliable, effective and comprehensive block of all the necessary nerves of upper limb. Ultrasound guided corner pocket approach is the recommended and most widely practiced technique for supraclavicular BPB. In this approach, a single injection of local anesthetic is given  at the angle formed between the first rib and inferolateral side of subclavian artery 1. The limitation of this approach, however, is the deeper location of T1 ventral ramus and inferior trunk compared to superior and middle trunks. This often results in inferior trunk (C8-T1, ulnar nerve) sparing. Previous studies, also concurred this and observed an ulnar nerve sparing of 5-30%  with this approach, which can result in incomplete anesthesia for  these surgeries.2-5

With the recent updates in ultrasound resolution, it is now feasible to isolate and locate all three trunks of brachial plexus. Dr Karmakar et al. recently described one such method called as Sequential Ultrasound Imaging Technique (SUIT) to identify all the three trunks.4,5  This enables us to block each trunk separately, making Selective Trunk Block (SeTB) a potential approach to provide comprehensive and complete anesthesia or analgesia for all the patients undergoing any upper limb surgery. In this technique, we sequentially identify ventral rami of all the roots and formation of all trunks of brachial plexus.6,7 After obtaining an appropriate ultrasound view, local anesthetic is deposited two sites – one between superior and middle trunk, another at the inferior trunk.

We therefore hypothesize that an approach to selectively identify and block all three trunks should be able to produce a comprehensive and complete anasethesia for all upper limb surgeries without ulnar nerve sparing common with corner pocket approach.

REFERENCES

  1. Soares LG, Brull R, Lai J, Chan VW. Eight ball, corner pocket: the optimal needle position for ultrasound-guided supraclavicular block. Reg Anesth Pain Med. 2007;32(1):94-95. doi:10.1016/j.rapm.2006.10.007
  2. Trivedi, Saurabh; Gupta, Srishti1; Bhardwaj, Hemendra; Sahoo, Tapan Kumar; Gupta, Seema; Trivedi, Gaurav2. Efficacy of intertruncal and corner-pocket approaches of ultrasound-guided supraclavicular block in terms of ulnar nerve blockade: A randomised controlled study. Indian Journal of Anaesthesia 67(9):p 778-784, September 2023. | DOI: 10.4103/ija.ija_45_23
  3. Kukreja P, Kofskey AM, Ransom E, et al. Comparison of Supraclavicular Regional Nerve Block Versus Infraclavicular Regional Nerve Block in Distal Radial Open Reduction and Internal Fixation: A Retrospective Case Series. Cureus. 2022;14(4):e24079. Published 2022 Apr 12. doi:10.7759/cureus.24079
  4. Fredrickson MJ, Patel A, Young S, Chinchanwala S. Speed of onset of ’corner pocket supraclavicular’ and infraclavicular ultrasound guided brachial plexus block: a randomised observer-blinded comparison. Anaesthesia. 2009;64(7):738-744. doi:10.1111/j.1365-2044.2009.05918.x
  5. Jo Y, Park J, Oh C, et al. Comparison of the ulnar nerve blockade between intertruncal and corner pocket approaches for supraclavicular block: a randomized controlled trial. Korean J Anesthesiol. 2021;74(6):522-530. doi:10.4097/kja.21028
  6. Karmakar MK, Pakpirom J, Songthamwat B, Areeruk P. High definition ultrasound imaging of the individual elements of the brachial plexus above the clavicle. Reg Anesth Pain Med. 2020;45(5):344-350. doi:10.1136/rapm-2019-101089
  7. Songthamwat B, Pakpirom J, Pangthipampai P, Vorapaluk P, Karmakar MK. Reliability of a sequential ultrasound imaging technique (SUIT) to identify the individual elements of the brachial plexus above the clavicle. Reg Anesth Pain Med. 2021;46(12):1107-1109. doi:10.1136/rapm-2021-102701

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • All adults posted for surgeries of distal humerus, elbow, forearm, wrist and hand.
  • Age group : 18-65 years
  • Body mass index of 18 to 35 kg/sq.m.

Exclusion Criteria

  • Patients not giving consent for the block
  • Patients not able to understand the procedure and risks associated with it
  • Known neuropathy or injury of musculocutaneous, radial, ulnar or median nerve
  • Abnormal neck or shoulder anatomy
  • Patients with decreased mentation or altered sensorium
  • Patients with any local site infection
  • Any other surgical contraindications for regional anaesthesia
  • ASA grade 3 or more
  • Patients with local anaesthetic allergy.

Outcomes

Primary Outcomes

Comparison of sensory blockade of median, radial, ulnar and musculocutaneous nerves in both groups

Time Frame: 5,10,15,20,25,30 minutes after nerve block

Secondary Outcomes

  • Comparison of motor blockade of median, radial, ulnar and musculocutaneous nerves in both groups(5,10,15,20,25,30 minutes after nerve block)
  • Comparison of time taken to perform block in both groups(During the nerve block)
  • Comparison of time taken to achieve sensory anaesthesia in both groups(5,10,15,20,25,30 minutes after nerve block)
  • Comparison of time taken to achieve motor blockade in both groups(5,10,15,20,25,30 minutes after nerve block)
  • Comparison of incidence of phrenic nerve palsy in each group(Baseline (before giving nerve block) and 30 minutes after nerve block)
  • Assessment of patient discomfort during the procedure by VAS score(During nerve block)
  • Success or feasibilty of discovering all three trunks in selective trunk block(During nerve block)

Investigators

Sponsor
Arshad Ayub
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Salma Suman P

All India Institute of Medical Sciences, New Delhi

Study Sites (1)

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