Blood Flow Change After Free Flap Surgery in Diabetic Patients

Completed

• Conditions: Diabetes

• Registration Number: NCT03027219
• Lead Sponsor: Asan Medical Center

Brief Summary

We aim to evaluate the flow change of arterial anastomosis site during free flap surgery in diabetic patients.

Detailed Description

Objective: flow change of arterial anastomosis site during free flap surgery in diabetic patients.

Background: No research was published about flow change of arterial anastomosis site of the free flap during surgery.

Plan: Using Duplex sonography, various parameters related flap perfusion will be evaluated before and after the administration of alprostadil.

Study Timeline

• Study First Submitted: 2017-01-18
• Study First Submitted QC: 2017-01-19
• Study First Posted: 2017-01-23
• Study Start: 2017-01-31
• Status Verified: 2018-11
• Primary Completion: 2018-11-02
• Study Completion: 2018-11-29
• Last Update Submitted: 2018-11-29
• Last Update Posted: 2018-11-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

1. Plan to receive free flap transfer under general anesthesia
2. Age: >=18 and <80 years old
3. History of diabetes mellitus
4. Administration of alprostadil during surgery
5. Volunteer, who are provided written informed consent prior to study participation

Exclusion Criteria

1. Refuse the participation of study
2. >= American society of anesthesiologist physical status IV
3. Use of any vasopressor or inotropic for hemodynamic instability before participation of study
4. Inappropriate subjects who are identified by researchers

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Flow change	before alprostadil administration, 30 mins after alprostadil administration	Peak velocity of anastomosis-site of free flap

Trial Locations

Locations (1)

Asan Medical Center; 🇰🇷 Seoul, Korea, Republic of