Contrast Nephropathy in Type 2 Diabetes
- Conditions
- Kidney Function Affection Upon Exposure to RadiocontrastDiabetesMicroalbuminuria
- Interventions
- Registration Number
- NCT03470454
- Lead Sponsor
- Fayoum University
- Brief Summary
To study the effect of radiocontrast material on kidney functions in diabetics with microalbuminuria
- Detailed Description
Study design:
This study will be an observational prospective cohort study.
Study population:
Diabetics undergoing any intervention using radiocontrast material for any medical indication in Fayoum universiy hospital will be selected. There will be two arms of the study,each arm will contain 20 patients first arm diabetics on linagelptin, second arm diabetics on other DPP4 inhibitors.
Data collection:
Patients will be subjected to; full clinical examination,waist hip ratio assessment,BMI assessment fasting blood glucose,Serum uric acid, urine ACR, eGFR will be done before and after the investigation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Diabetics on DPP 4 inhibitor treatment
- Diabetics on insulin
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description diabetics on other DPP4 inhibitors Linagliptin Oral Tablet Diabetic pateints were given other DPP4 inhibitors eg: vlidagliptin for blood glucose control diabetics on linagelptin Linagliptin Oral Tablet Diabetic patients were given linagelptin for blood glucose control
- Primary Outcome Measures
Name Time Method affection of estimated glomerular filtration rate Two months A significant decrease in estimated glomerular filtration rate (eGFR)
- Secondary Outcome Measures
Name Time Method change in serum uric acid Two months A significant rise in serum uric acid
Trial Locations
- Locations (2)
Faculty of medicine Fayoum univesity
🇪🇬Fayoum, Egypt
Fayoum University
🇪🇬Fayoum, Egypt