PENG Block vs. ESP Block for Pediatric Hip Surgery

Phase 4

Completed

• Conditions: Hip Dysplasia; Hip Injuries; Hip Disease; Hip Fractures
• Interventions: Drug: Pericapsular nerve group block using 0.2% ropivacaine; Drug: Erector Spinae Plane Block using 0.2% ropivacaine; Other: Standard care

• Registration Number: NCT06087549
• Lead Sponsor: Poznan University of Medical Sciences

Brief Summary

The study compares the effectiveness and safety of the pericapsular nerve blockade vs. ESPB in pediatric patients who underwent hip surgeries.

Detailed Description

The study compares the effectiveness and safety of the pericapsular nerve blockade vs. ESPB in pediatric patients who underwent hip surgeries. In addition, we aim to determine the optimal volume of local anesthetics needed to achieve a satisfactory level of analgesia.

Study Timeline

• Study First Submitted: 2023-07-05
• Study First Submitted QC: 2023-10-11
• Study Start: 2023-10-17
• Study First Posted: 2023-10-17
• Status Verified: 2024-02
• Primary Completion: 2024-02-23
• Study Completion: 2024-02-23
• Last Update Submitted: 2024-02-26
• Last Update Posted: 2024-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• pediatric patients aged between 0-12 years who will undergo hip surgery

Exclusion Criteria

• a history of chronic pain use of gabapentin/pregabalin for > 3 months opioid use > 1 repeated opioid prescription in the last three months
• morbid obesity (BMI > 99th percentile)
• Infection at block application area
• coagulopathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Pericapsular nerve group block (PENG) group	Pericapsular nerve group block using 0.2% ropivacaine	regional anesthesia: spinal anesthesia - 0,1ml/kg 0,5% ropivacaine + PENG block - 0.5mL/kg 0.2% ropivacaine, max. 20mL
Erector Spinae Plane Block (ESPB) group	Erector Spinae Plane Block using 0.2% ropivacaine	regional anesthesia: spinal anesthesia - 0,1ml/kg 0,5% ropivacaine + ESP block - 0.5mL/kg 0.2% ropivacaine, max. 20mL
Control group	Standard care	regional anesthesia: spinal anesthesia - 0,1ml/kg 0,5% ropivacaine

Primary Outcome Measures

Name	Time	Method
FLACC score	48 hours after surgery	The FLACC scale or Face, Legs, Activity, Cry, Controllability Scale is used to assess pain for children between the ages of 2 months and seven years or individuals unable to communicate their pain. The scale is scored in a range of 0-10, with 0 representing no pain.

Secondary Outcome Measures

Name	Time	Method
NLR	48 hours after surgery	neutrophil-to-lymphocyte ratio
total opioid consumption	48 hours after surgery	morphine equivalents in miligrams
PLR	48 hours after surgery	platelet-to-lymphocyte ratio

Trial Locations

Locations (1)

Department of Spine Diseases and Pediatric Orthopedics, University of Medical Sciences, Poznań, Poland; 🇵🇱 Poznań, Wielkopolska, Poland