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Improving the design of insoles for diabetic foot disease

Completed
Conditions
Diabetes with peripheral neurpathy
Nutritional, Metabolic, Endocrine
Diabetes mellitus
Registration Number
ISRCTN19805071
Lead Sponsor
Glasgow Caledonian University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
20
Inclusion Criteria

1. 18-75 years of age
2. Shoe size 5-11 (UK)
3. Able to walk 300m (including ~20m barefoot) safely
4. Diabetes mellitus Type 1 or 2 with duration =10 years
5. Diabetic peripheral neuropathy defined as loss of sensation to 10g monofilament test at one or more forefoot sites
6. Elevated barefoot plantar pressure (>700kPa) measured at the forefoot during walking

Exclusion Criteria

1. Lower limb, foot or digital amputation (at a level proximal to the distal IPJ, or involving the hallux)
2. Severe callus (callus will not result in exclusion if it has been reduced to a level that does not affect sensation of underlying skin)
3. History of medical conditions, injuries or surgical procedures that significantly influence gait, or which cause pain on walking (including Charcot)
4. Severe foot deformity or reduction in ROM that result in abnormal gait or preclude good fit of study shoe (including Charcot)
5. Severe concurrent medical condition that would prevent participation in study procedures (e.g. severe cardiac/pulmonary condition that precludes activity) or with life expectancy = 3 months.
6. Pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Forefoot peak plantar pressure, measured using an in-shoe plantar pressure measurement system (Pedar, Novel GmbH, Munich) at a single timepoint immediately after the insoles are provided to the patient
Secondary Outcome Measures
NameTimeMethod
Validation of computational models in this patient population comparing the predicted plantar pressures to those measured experimentally
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