Control in the Hospital by Extensive Clinical rules for Unplanned hospitalisations in elderly Patients.

Recruiting

• Conditions: medication safety; readmission; clinical rules; medication review; CDSS

• Registration Number: NL-OMON21393
• Lead Sponsor: Gerontopharmacology, Zuyderland Medical Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 2400

Inclusion Criteria

The study population consists of older people admitted unplanned to the hospital and fulfilling the following criteria: 1) aged 60 years and over, 2) ability to give informed consent, 3) polypharmacy (> 5 drugs chronically), 4) at least two signals from the trigger list as proposed by the report Eindrapport medicatieveiligheid.

Exclusion Criteria

The intention of the study is to include the normal population offered to the hospital as much as possible. However, due to legal constraints and to avoid certain biases potential subjects who meets any of the following criteria will be excluded from participation in this study: intentional intoxications, patients treated with cytostatics, patients with a life expectancy of less than 3 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint is the number of readmissions during the year after admission. An economic evaluation and quality of life analysis is part of the proposal.

Secondary Outcome Measures

Name	Time	Method
Secondary endpoints of this study are; number of emergency department contacts, number of nursing home admissions during the year after patients’ inclusion in the study, death, time to hospital readmission, the number of hospital readmissions during the following 30, 180 and 365 days, the number of medication-related hospital (re) admissions, the combined endpoint hospital readmissions, emergency department contacts, nursing home admissions or death, total costs (from a societal perspective) and the Quality Adjusted Life Years (QALY) score.