Preventing Deoxygenation With High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery: A Randomized Controlled Trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease
- Sponsor
- Alexandria University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- arterial partial pressures of oxygen
- Last Updated
- 5 years ago
Overview
Brief Summary
High-flow nasal cannula (HFNC) is a device that delivers10 to 70 L min-1 of heated, humidified 100% oxygen via nasal route. It provides positive airway pressure, decreases dyspnea, decreases the work of breathing, and improves comfort
Detailed Description
Beneficial effects of the HFNC system have been assessed based on 3 physiologic conditions: decreased dead space, a high concentration of inspiratory oxygen, and positive pressure in the oro-laryngeal cavity.Studies have shown that it improves oxygenation in various perioperative settings such as the apneic patients, patients with respiratory failure , and patients undergoing bronchoscopy
Investigators
rehab zayed
Assisstant Professor of Anesthesia
Alexandria University
Eligibility Criteria
Inclusion Criteria
- •ASA physical status II and III,
- •undergoing VATS
Exclusion Criteria
- •refusal of patients
- •extrem of age
Outcomes
Primary Outcomes
arterial partial pressures of oxygen
Time Frame: two hours
an arterial blood sample will be taken after induction of anaesthesia then every 10 min till the end of the operation.
pH measurement
Time Frame: two hours
an arterial blood sample will be taken after induction of anaesthesia then every 10 min till the end of the operation.