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临床试验/NCT04520568
NCT04520568Unknown2 期

Preventing Deoxygenation With High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery: A Randomized Controlled Trial

Alexandria University2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年8月1日最近更新:
适应症

试验速览

阶段
2 期
入组人数
60
试验地点
2
主要终点
arterial partial pressures of oxygen

研究概览

简要总结

High-flow nasal cannula (HFNC) is a device that delivers10 to 70 L min-1 of heated, humidified 100% oxygen via nasal route. It provides positive airway pressure, decreases dyspnea, decreases the work of breathing, and improves comfort

详细描述

Beneficial effects of the HFNC system have been assessed based on 3 physiologic conditions: decreased dead space, a high concentration of inspiratory oxygen, and positive pressure in the oro-laryngeal cavity.Studies have shown that it improves oxygenation in various perioperative settings such as the apneic patients, patients with respiratory failure , and patients undergoing bronchoscopy

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
Single (Participant)

入排标准

年龄范围
30 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ASA physical status II and III,
  • undergoing VATS

排除标准

  • refusal of patients
  • extrem of age

结局指标

主要结局

arterial partial pressures of oxygen

时间窗: two hours

an arterial blood sample will be taken after induction of anaesthesia then every 10 min till the end of the operation.

pH measurement

时间窗: two hours

an arterial blood sample will be taken after induction of anaesthesia then every 10 min till the end of the operation.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

rehab zayed

Assisstant Professor of Anesthesia

Alexandria University

研究点 (2)

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