ISRCTN07355119已完成3 期
A randomised trial to evaluate whether treatment can be reduced without compromising effficacy in a low risk group of patients defined by a molecular minimal residual disease (MRD) technique; and to evaluate whether further post-remission intensification can improve outcome for a MRD-defined high risk group
niversity of Sheffield (UK)0 个研究点目标入组 2,500 人开始时间: 2003年8月18日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 2,500
研究概览
简要总结
2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/23395119 2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24904116 2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24924991 2017 retrospective observational analysis in: http://www.ncbi.nlm.nih.gov/pubmed/28982824 2018 results in: http://www.ncbi.nlm.nih.gov/pubmed/29519867 (added 02/08/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Children aged 1 - 18 years with ALL
- •As of 12/02/2010, young adults up to their 25th birthday are also eligible for this trial.
排除标准
- •1. Mature B ALL
- •2. Infant ALL (aged less than 1 year)
- •3. Philadelphia positive ALL
研究者
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