ISRCTN93280043已完成不适用
A randomised controlled trial to evaluate whether a short course of once weekly risedronate prevents bone loss following high-dose steroid therapy for an acute exacerbation of inflammatory bowel disease
niversity Hospitals Bristol NHS Foundation Trust (UK)0 个研究点目标入组 100 人开始时间: 2008年11月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aged greater than or equal to 16 years, either sex
- •2. Ulcerative colitis and Crohn's disease
- •3. Experiencing a relapse
- •4. Requiring steroid therapy
排除标准
- •1. Aged under 16 years
- •2. Use of corticosteroids in the preceding 3 months
- •3. Evidence of osteoporosis (known vertebral fracture, T score less than -2.5)
- •4. Pregnant and lactating women
- •5. Women of childbearing age will be eligible provided they use reliable contraception
- •6. Bone active therapy within previous 12 months (excluding calcium and low dose vitamin D)
- •7. Previous treatment with a bisphosphonate at any time
- •8. Associated disorder which may influence bone metabolism
- •9. Lactose intolerance
研究者
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