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临床试验/CTRI/2024/06/068597
CTRI/2024/06/068597尚未招募2 期

An Experimental Study To Ascertain The Effectiveness Of Individualized Homoeopathic Medicine In Cases Of Chronic Urticaria

Rajkot Homoeopathic Medical College Parul University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年6月17日最近更新:
适应症
相关药物

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
To ascertain effectiveness of Individualized Homoeopathic Medicines in chronic urticaria.

研究概览

简要总结

Chronic urticaria is common in every country globally, and affects 1% of world population of all ages, it’s prevalence has increased to 2-10 fold over last decade .Its prevalence is 4.4% in overall point, out of which 1.5% is in Asia. The mean age of onset is in their late twenties to forties. It is more common at age less than 18 yrs that is about 1.4%. Patients aged more than or equal to 65 years represent prevalence of 10-21.7%.Chronic Urticaria is more common in women up to 80%, but these gender difference is not apparent in children under 15 yrs. Chronic urticaria can occur with angioedema also. Angioedema is reported in approx 40-60% of patients with Chronic urticaria. Chronic Spontaneous urticaria leads to impairment of sleep and cognitive functions and has major impact on social interactions, work performances; daily life functions including inter-personal relationships. Among other skin disorders, Chronic Urticaria is those with highest Health Related Quality Of Life (HRQoL) impairment. Main factors responsible for physical, social, and emotional impact of Chronic Urticaria include the sudden and unpredictable appearance of wheals, angioedema and itch which is very distressing and has major impact on sleep and patients well being. Allopathic treatment for urticaria is antihistamines. But Only 50% patients with Chronic Urticaria have adequate response to antihistamines. Remission rate of Chronic urticaria in adults is 20-75% within 1 year. Resolution rate in children is also very low with studies reporting remission rates in 19% at every year. Homoeopathy focuses on treating man as a whole and not just symptoms of urticaria. It believes in individualization, and law of similia. It does not belief in treating it superficially but treats disease from its root .It offers effective treatment in acute, recurrent and chronic urticaria. As Urticaria is an expression of internal disturbance and hypersensitive reaction reflected on skin. In APH 187 -190 Dr. Hahnemann says “local disease without any external cause is due to some internal disturbance and requires internal malady for their cure.” Medicines are selected on basis of symptom similarity in each suffering individual. It when taken reduces hypersensitivity to allergen and reduces dependency on antihistamine.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
15.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • •Age- 15-70 years.
  • •Sex- male and female both will be included.
  • •Prediagnosed cases of urticaria will be selected.
  • •New cases will be selected on basis of definition of Chronic urticaria.
  • •Only those cases which had an onset since 2 months and are not autoimmune in origin will be taken.

排除标准

  • •Age:-less than 15 and more than 70 yrs.
  • •Those patients who had/ have any episode of angioedema with urticaria.
  • •Patients with chronic urticaria who are on other therapeutic measures.
  • •Patients having any other comorbidities.
  • •Patients who will not maintain regular follow up.

结局指标

主要结局

To ascertain effectiveness of Individualized Homoeopathic Medicines in chronic urticaria.

时间窗: it will be achieved within 9 months of period

次要结局

  • To assess improvement in patients of urticaria after administrating homoeopathic medicines(with the help of UAS7 TWICEDAILY ASSESMENT (urticaria activity score).)

研究者

发起方
Rajkot Homoeopathic Medical College Parul University
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Meeti Gokani

Rajkot Homoeopathic Medical College, Parul University

研究点 (1)

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