Pre-operative chemotherapy with FOLFOX4 in potentially resectable liver metastases from colorectal origin. Pilot phase II study
Not Applicable
- Conditions
- patients with liver metastasis from colon cancer
- Registration Number
- JPRN-UMIN000000740
- Lead Sponsor
- OGSG
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1. cavity fluid which should be taken out 2. with double cancer and/or multiple cancer which excludes carcinoma in situ 3. with peripheral nerve disorder 4. with infectious disease 5. under the condition of diarrhea (watery diarrhea) 6. with psychological disorder which disturb the entry to the study 7. under continuous steroids therapy 8. with other severe diseases (pulmonary fibrosis, cardiac failure, liver dysfunction, renal dysfunction, intestinal paralysis/obstruction or uncontrolled DM) 9. pregnant and/or nursing women 10. with allergic history against medicines 11. doctors' stop not to register to the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Resection rate on the liver
- Secondary Outcome Measures
Name Time Method Rate of completion on preoperative chemotherapy Adverse events Response rate Time to progression