Does ablation of genicular nerves (nerves around knee joint) with radiofrequency ablation technology provide more relief than traditional steroid joint injections for relief from pain in osteoarthritis of knee joint?

Phase 4

• Conditions: Health Condition 1: M179- Osteoarthritis of knee, unspecified

• Registration Number: CTRI/2023/11/059963
• Lead Sponsor: AIIPMR

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 19 December 2023

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patients of either sex with primary OA of one or both knees fulfilling diagnostic criteria for OA knee laid down by American College of Rheumatology

2. Kellgren-Lawrence (radiologic criterion) score of at least 3

3. Chronic knee pain with pain intensity of at least 4 out 10 on the NRS on most or all days for more than 3 months, resistant to conventional therapy including non-steroidal anti-inflammatory drugs, opioids, muscle relaxants, oral steroids, physical therapy and intra-articular injection.

4. In patients with bilateral knee OA, the most painful side will be studied.

5. Age 40-70 years

Exclusion Criteria

1. Patients with secondary OA of knees (ie, rheumatoid arthritis or gouty arthritis)

2. Any knee treatment with steroids, methotrexate or azathioprine; previous RF ablation treatment for similar symptoms; intra-articular knee corticosteroid or hyaluronic acid injection in the past 3 months

3. active systemic or local infections at the site of proposed needle and electrode placement;

4. coagulopathy or other bleeding disorder;

5. cognitive deficit; unstable medical or psychiatric illness;

6. Previous knee joint replacement surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified