Aneuploidy Rate and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH
Not Applicable
Terminated
- Conditions
- Aneuploidy Rate
- Interventions
- Procedure: Stimulation with human FSHProcedure: Stimulation with recombinant FSH
- Registration Number
- NCT01164943
- Lead Sponsor
- IVI Madrid
- Brief Summary
Several stimulation protocols have been used in in vitro fertilization (IVF) in a cycle of egg donation; recombinant FSH and human FSH are included. The effect of each kind of hormone on aneuploidy rate it is unknown. If there was an increase on aneuploidy rate of one of these stimulation protocols, there will be a negative effect on the successful rates in the egg donation cycles. The aim of this study is to observe if there is a different in aneuploidy rate and morphological oocyte parameters between different stimulation protocols.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- Egg donation cycles with more than 8MII in oocyte retrieval day
Exclusion Criteria
- Male factor
- Uterine malformations
- genetic alterations
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Human FSH Stimulation with human FSH - Recombinant FSH Stimulation with recombinant FSH -
- Primary Outcome Measures
Name Time Method Aneuploidy Rate 2011 January Analysis of all nuclei fixed
- Secondary Outcome Measures
Name Time Method Outcome rates (implantation, pregnancy and miscarriage rate) 2011 April Time requierd to know all the implantation, pregnancy and miscarriage rate
Oocyte morphology 2011 january Analysis of all oocytes
Trial Locations
- Locations (1)
Insituto Valenciano de Infertilida, Spain, Madrid
🇪🇸Madrid, Spain