Effectivity of different oxygen therapy devices in patients with chronic lung disease in the inflight environment: oxygen cylinders vs. oxygen concentrators

Not Applicable

• Conditions: J44.9; Chronic obstructive pulmonary disease, unspecified

• Registration Number: DRKS00004257
• Lead Sponsor: Medizinische Klinik Innenstadt, Pneumologie, Universität München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-07-30
• Study Start: 2012-07-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

COPD Grade II / III according GOLD guidelines
stable phase of disease
living in Munich
subjective feeling that weather does influence the disease

Exclusion Criteria

- concurrent severe disease (as dementia, carcinoma, right heart failure, stroke, myocardial infarction)
- continuous oxygen therapy
- high altitude fear
- reduced PaO2 < 60 mmHg
- increased PaCO2 > 50 mmHg
- patients with emphysema (intrathoracic gas volume larger 130 % predicted)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main study objective was the arterial oxygenation after 30 min of exposure with each of the tested devices or after room air at 2650 m. Oxygenation was evaluated by blood gases from the arterialised ear lobe (PaO2, partial oxygen pressure).

Secondary Outcome Measures

Name	Time	Method
Oxygen saturation (SaO2) was measured by pulse oxymetrie after 30 min of exposure with one of the tested devices or with room air at 2650 m. Carbon dioxide partial pressure (PaCO2) was assessed together with the primary outcome (PaO2) by arterial blood gas measurement.