Effect of Coffeeberry on Mood, Motivation and Cognitive Performance

Not Applicable

Completed

• Conditions: Cognitive Performance; Fatigue, Mental; Alertness; Mood; Motivation
• Interventions: Dietary Supplement: Cherry-flavored still beverage; Other: Placebo cherry-flavored still beverage

• Registration Number: NCT04974606
• Lead Sponsor: PepsiCo Global R&D

Brief Summary

The primary purpose is to test the short-term effects of the acute consumption of two novel beverages made from coffeeberries, the fruit of the coffee plant (Coffea arabica) benchmarked against caffeine on several aspects of cognitive performance.

Preliminary studies suggest that flavanols and chlorogenic acids can enhance cognitive performance. It is unknown if drinks formulated with flavanols and chlorogenic acids (without high sugar or caffeine) improve cognition or mood to a similar extent as caffeine. Coffeeberry beverage comparisons will be made to a flavored positive control beverage containing caffeine and a flavored placebo beverage.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06-28
• Primary Completion: 2016-12-16
• Study Completion: 2016-12-16
• Status Verified: 2021-07
• Study First Submitted: 2021-07-09
• Study First Submitted QC: 2021-07-13
• Last Update Submitted: 2021-07-13
• Study First Posted: 2021-07-23
• Last Update Posted: 2021-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Are older than 17 and under 50 years of age
• Self-report of good health

Exclusion Criteria

• Using any prescription medication including birth control
• Report hypersensitivity to caffeine
• Have visual impairment that cannot be corrected with glasses or contact lenses
• Report any food allergies
• Self-reported excessive leisure time physical activity (> 7 strenuous bouts per week)
• the presence of current gastrointestinal, sleep, or psychiatric disorder,
• Report pregnancy/lactation, illegal drug use, smoker
• failure to demonstrate adequate minimal performance on lab, computer-based cognitive tasks.
• Participation in another clinical trial within past 30 days

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Caffeine 75 mg beverage	Cherry-flavored still beverage	Appearance-matched to the other beverages
Coffeeberry 100 mg beverage	Cherry-flavored still beverage	Appearance-matched to the other beverages
Coffeeberry 300 mg beverage	Cherry-flavored still beverage	Appearance-matched to the other beverages
Placebo beverage	Placebo cherry-flavored still beverage	Appearance-matched to the other beverages

Primary Outcome Measures

Name	Time	Method
Motivation score	Change from baseline to 60 and 120 min post-consumption. Higher motivation score is better.	Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)
Energy score	Change from baseline to 60 and 120 min post-consumption. Stronger feelings of mental and physical energy are better.	Subjective mental and physical state energy and fatigues scales (EFS-State Scale). Composite scores range from 0 to 300 mm, from feelings of no energy to strongest feelings of energy during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS)
Cognition score	Change from baseline to 60 and 120 min post-consumption. Higher test scores are better.	Objective Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS) for word and picture presentation and recall, serial 3 and 7 subtraction, Rapid Visual Information Processing (RVIP).
Fatigue score	Change from baseline to 60 and 120 min post-consumption. Lower fatigue score is better.	Subjective Visual Analog Scale (VAS) rating from 1-100 mm from not at all to extremely, during Cognitive Demand Battery (CDB) using Computerised Mental Performance Assessment framework tasks (COMPASS)
Calmness score	Change from baseline to 60 and 120 min post-consumption. Higher calmness score is better.	Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)
Alertness score	Change from baseline to 60 and 120 min post-consumption. Higher alertness score is better.	Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)
Contentedness score	Change from baseline to 60 and 120 min post-consumption. Higher contentedness score is better.	Subjective Bond-Lader Visual Analog Scale (VAS) rating from 1-100 mm representing the full range of each dimension from not at all to extremely, during Cognitive Demand Battery (CDB)during Cognitive Demand Battery (CDB) Visual Analog Scale (VAS) rating from 1-100 mm during Cognitive Demand Battery(CDB) within Computerised Mental Performance Assessment framework tasks (COMPASS)

Trial Locations

Locations (1)

Exercise Psychology Laboratory University of Georgia; 🇺🇸 Athens, Georgia, United States