Clinical study on the effect of invigorating spleen and warming kidney on renal tubular injury in patients with chronic heart failure

Guang'anmen Hospital, China Academy of Chinese Medicine Science0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•(1) Age from 30 to 80, gender unlimited;
•(2) It meets the diagnostic criteria for CHF;
•(3) Urine N-acetyl-ß-D-glucosaminosidase (NAG) > 12U/L, and estimated glomerular filtration rate (EGFR) BBB> mL /min/1.73m2;
•(4) It meets the diagnostic criteria of the syndrome of insufficiency of spleen and Yang;
•(5) the cardiac function class (NYHA) II - III;
•(6) Signed the informed consent.

•(1) Heart failure caused by valvular heart disease, congenital heart disease, myocarditis, cardiomyopathy, etc.;
•(2) People who have been diagnosed with kidney disease;
•(3) Severe arrhythmias, including frequent premature ventricular beats, grade II type II atrioventricular block, grade III atrioventricular block, and cardiogenic shock;
•(4) Patients with severe hypertension and poor medication control (SBP >= 180mmHg and/or Diastolic blood pressure >= 110mmHg);
•(5) Patients with severe liver function abnormalities (ALT or AST reaching more than 3 times the upper limit of normal value), endocrine diseases, malignant tumors and autoimmune diseases;
•(6) Pregnant or lactating women;
•(7) People with allergic constitution and drug components in this study;
•(8) Participating in other clinical trials or participating in clinical trials of other drugs for less than one month.

发起方

Guang'anmen Hospital, China Academy of Chinese Medicine Science