NCT00513201已完成4 期
Lyspro Insulin vs Regular Insulin in Cirrhotic Patients
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 试验地点
- 2
- 主要终点
- Glycemic control in lyspro vs regular insulin treated patients
研究概览
简要总结
OBJECTIVE: To compare lispro insulin and regular insulin in the glycemic control of patients with liver cirrhosis and type 2 diabetes subjects. METHODS: 108 patients with liver cirrhosis and type 2 diabetes were randomly treated with regular insulin or lispro. After 122 weeks a cross-over was carried out and patients followed-up for 122 weeks. Then, all patients received a standard breakfast of 145 kcal following 12 U.I. of regular insulin or lispro, and C-peptide and insulin serum levels were determined over 300 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Double
入排标准
- 年龄范围
- 48 Years 至 67 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Insulin-treated diabetes mellitus and liver cirrhosis
排除标准
- •Oral hypoglycemic agents treated diabetes mellitus
- •Liver cancer
结局指标
主要结局
Glycemic control in lyspro vs regular insulin treated patients
Glycemic control in lyspro vs regular insulin in cirrhotic patients
次要结局
- Tolerance to treatment and reduced postprandial hypoglycemia episodes
研究者
研究点 (2)
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