A prospective study evaluating efficacy of ALA HCl for diagnosis of upper urinary tract urothelial carcinoma
- Conditions
- pper urinary tract urothelial carcinoma
- Registration Number
- JPRN-UMIN000031205
- Lead Sponsor
- Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
- Brief Summary
Based on the results for these 18 patients, the sensitivity and specificity of ALA-PDD were calculated to be 80.0% and 33.3%, respectively, whereas for white light observation the respective values were 86.7% and 66.7% (Table 2). The PPV and NPV of ALA-PDD were 59.5% and 70.0%, respectively. The combined observation had the highest sensitivity at 72.5%, but the lowest specificity at 51.9%.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Not provided
Patients with allergy to ALA HCl or porphyrin, light hypersensitivity Patients with administration of the drugs which are contraindicated contraindication with ALA HCl Pregnant or lactating woman Patients with severe underlying diseases such as cardiovascular event, liver disfunction, diabetes mellitus, and so on. Patients who have been enrolled into another study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method