Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 51
- 试验地点
- 4
- 主要终点
- Change from baseline using the Numeric Rating Scale for Pain at 1 hour
研究概览
简要总结
The purpose of these study is to compare the effectivity of the Median Nerve Neural Mobilization technique to the complete absence of treatment in a group of patients who suffer cervicobrachial pain.
详细描述
Median Nerve Neural Mobilization (MNNM) is a non invasive physical therapy technique that achieves pain relief through mechanical stimulation of the Median Nerve and the brachial plexus. It is believed that the hypoalgesic effect offered by the neural tissue mobilization procedure is a consequence of descending nervous system pain modulation activity and an improvement in the distinct biomechanical and sensitive properties of the involved neural tissue. The neural tissue mobilization procedure is associated to an increase in nerve mobility, edema, inflammation and intraneural pressure reduction without any known side effects when applied properly which is an important contrast to the wide variety of side effects caused by commonly used drug therapy to treat cervicobrachial pain.
Despite the crescent interest among the scientific community in evidence based options to treat pain there is a current lack of enough controlled double blind clinical trials that measure the effectiveness of neural tissue mobilization techniques such as the (MNNM) and its specific effect over cervicobrachial pain. For this reason the present investigation consisted in the application of a treatment protocol based on Median Nerve Neural Mobilization in a controlled double blind clinical trial with the aim to assess its clinical effectiveness in treating pain symptoms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of cervicobrachial pain confirmed by magnetic resonance imaging
- •Presence of unilateral symptoms of arm pain, paresthesia or numbness in the upper extremity during at least 3 continuous months previous to the application of treatment.
- •Positive results in all of the following tests: Spurling, Distraction, and Upper Limb
排除标准
- •Contraindication in the use of nonsteroidal anti-inflammatory drugs (NSAIDs)
- •The use of any type of treatment, therapy, procedure or drug to relieve pain
- •Patients who are under anticonvulsant, antidepressant or psychotropic medication
- •Vertebral instability
- •Vertebral osteoporosis
- •Vertebral or spine infection.
- •Neurologic diseases of genetic, infectious or neoplastic origin
- •Cervical stenosis myelopathy
- •Pregnancy
- •Kinesiophobia
- •Endocrine disorders and menopause
- •History of spine surgery
- •Intellectual disability, severe mental illness, intoxication, severe sleep deprivation, Alzheimer's disease.
研究组 & 干预措施
Median Nerve Neural Mobilization
15 minute Median Nerve Neural Mobilization sessions 3 times a week during 6 continuous weeks.The maximum degree of elbow extension applied in the Median Nerve neural mobilization procedure was determined through the use of a Universal Goniometer Device.
干预措施: Median Nerve Neural Mobilization (Procedure)
Median Nerve Neural Mobilization
15 minute Median Nerve Neural Mobilization sessions 3 times a week during 6 continuous weeks.The maximum degree of elbow extension applied in the Median Nerve neural mobilization procedure was determined through the use of a Universal Goniometer Device.
干预措施: Goniometer (Device)
Waiting list control group
Patients assigned to a 6 week waiting list to receive treatment
干预措施: Median Nerve Neural Mobilization (Procedure)
Waiting list control group
Patients assigned to a 6 week waiting list to receive treatment
干预措施: Goniometer (Device)
结局指标
主要结局
Change from baseline using the Numeric Rating Scale for Pain at 1 hour
时间窗: at baseline for both arms and 1 hour after the application of treatment only in the experimental arm, corresponding to intervention days 1, 9 and 18.
the Numeric Rating scale for Pain (NRS) is an 11 point scale for patient self reporting of pain in which 0 points represents the total absence of pain and 10 points the worst state of pain, it was employed to evaluate the presence and relieve of cervicobrachial pain symptoms.
次要结局
- Change from baseline of the Physical function involving the affected upper limb using the Quik DASH Scale(at baseline, corresponding to intervention days 1 and 18 of treatment)
- Cervical Rotation Range of Motion (CROM)(at baseline for both arms and 1 hour after the application of treatment only in the experimental arm, corresponding to intervention days 1 and 18 .)
研究者
Francisco Unda Solano
PHD Student
Universidad Europea de Madrid