Impact of Alarm Reduction on Delirium in ICU

Terminated

• Conditions: Delirium

• Registration Number: NCT04246892
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

Delirium is an acute and fluctuating disturbance of consciousness and can occur in 80% of critically ill patients. Delirium is more frequent in mecanically ventilated patients and is associated with longer hospital stay, increased cognitive impairment and mortality. On the occasion of the change of the monitors in the ICU ward, allowing a total withdrawal of alarms in patients room, this study evaluates the prevalence of delirium before and after the alarm withdrawal. During the first period the patients will be monitored as usual, and during the second period patients will be monitored without alarms ringing in patients room. Delirium will be screened with a validated, clinical tool.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-01-20
• Study First Submitted QC: 2020-01-28
• Study First Posted: 2020-01-29
• Study Start: 2020-02-03
• Primary Completion: 2023-02-23
• Study Completion: 2023-02-23
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-29
• Last Update Posted: 2023-08-30

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 89

Inclusion Criteria

• age>18 years, admission to ICU

Exclusion Criteria

• length of stay in ICU<24 hours, moribund patient, deafness, dementia, psychiatric pathology, delirium at admission, acute neurological pathology at admission (stroke, epilepsy, neuro-infection), hepatic encephalopathy, admission for cardiac arrest, admission for voluntary drug intoxication, pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
prevalence of delirium, according to a ICDSC score>3	at the end on the ICU stay, an average of 6 days	prevalence of delirium in each group

Secondary Outcome Measures

Name	Time	Method
length of stay in ICU (days)	at the end on the ICU stay, an average of 6 days
prevalence of sub-syndromic delirium in each group, according to a ICDSC score<4 and absence of delirium	at the end on the ICU stay, an average of 6 days
length of mecanical ventilation (days)	at the end on the ICU stay, an average of 6 days
in patients presenting a delirium, duration of delirium (days) defined by the number of days with a ICDSC score>3	at the end on the ICU stay, an average of 6 days

Trial Locations

Locations (1)

CHRU Nancy; 🇫🇷 Nancy, France